IFI16 Antibody
Product Details
- Cat. No.
- 200210
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chimpanzee, Human, Monkey
- Antigen: Recombinant protein encompassing the PAAD domain (aa 6-102) of human IFI16.
- Isotype: Rabbit Ig
- Gene: Q16666
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)