Product & ReviewsAntibodies
IFNAR1 (Ser535/539) Antibody
Product Details
- Cat. No.
- 252551
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Interferon-a Receptor, Type I, Subunit I (IFNAR1) associates with IFNAR2 to form the type I interferon receptor. This interferon receptor is a receceptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Down regulation of IFNAR1 is influenced by phosphorylation of Serine 535 and 539.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Dog (Canine), Human, Monkey, Mouse, Rat, Sheep (Ovine)
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser535/539 of human interferon-a receptor, type I, subunit I.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: P17181
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)