Product & ReviewsAntibodies

IgD-FITC, IA6-2, 50 Tests, RUO

Product Details

Cat. No.
B30652
Type
Flow Cytometry Reagents
Clonality
Monoclonal
Host
Mouse
Beckman Coulter Life Sciences

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Description

IgD, a member of the immunoglobulin (Ig) family, is expressed in naïve B cells. It exists in a transmembrane and a soluble form. IgD is, together with IgM, the first antibody isotypes expressed during B cell ontogeny. Bone marrow B cell precursors acquire surface IgM after assembling heavy (H) and light (L) chain variable region exons from prototypic variable (V), diversity (D) and joining (J) gene segments through an antigen-independent process. After leaving the bone marrow to colonize secondary lymphoid organs, B cells acquire surface IgD of the same specificity as surface IgM through alternative splicing of a pre-messenger RNA comprising V(D)J and both heavy chain constant μ (Cμ) and Cδ exons.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: IgD
  • Clone: IA6-2
  • Conjugate: FITC
  • Isotype: IgG2a

Handling

  • Quantity: 50 tests

Applications

  • Flow Cytometry (FC)
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