IgD-PE, IA6-2, 50 Tests, RUO
Product Details
- Cat. No.
- B30653
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
IgD, a member of the immunoglobulin (Ig) family, is expressed in naïve B cells. It exists in a transmembrane and a soluble form. IgD is, together with IgM, the first antibody isotypes expressed during B cell ontogeny. Bone marrow B cell precursors acquire surface IgM after assembling heavy (H) and light (L) chain variable region exons from prototypic variable (V), diversity (D) and joining (J) gene segments through an antigen-independent process. After leaving the bone marrow to colonize secondary lymphoid organs, B cells acquire surface IgD of the same specificity as surface IgM through alternative splicing of a pre-messenger RNA comprising V(D)J and both heavy chain constant μ (Cμ) and Cδ exons.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: IgD
- Clone: IA6-2
- Conjugate: PE
- Isotype: IgG2a
Handling
- Quantity: 50 tests
Applications
- Flow Cytometry (FC)