Product & ReviewsAntibodies
IgE (Dε2)-UNLB, E124.2.8, 0.2 mg, ASR
Product Details
- Cat. No.
- A40174
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The anti-IgE mAb binds to circulating IgE as well as to IgE antibodies bound to the low affinity receptor FcεRII (expressed mainly on eosinophils, B lymphocytes), or to the high affinity receptor FcεRI (expressed on mast cells, basophils, monocytes and monocytes-derived cells). The anti-IgE antibody induces the histamine release from basophils. However, it is known in the literature information that basophils from 10% to 20% of donors completely fail to release histamine in response to anti-IgE, designated anti-IgE "non releasers".
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: IgE (Dε2)
- Clone: E124.2.8
- Conjugate: Purified
- Isotype: IgG1
Handling
- Quantity: 0.2 mg
Applications
- Flow Cytometry (FC)