IHOG (3G8) Antibody
Product Details
- Cat. No.
- 253017
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
IHOG (Interference hedgehog) is a type 1 membrane protein mediates response to the active Hedgehog (Hh) protein signal. Ihog mutations produce defects characteristic of Hh signaling loss in embryos and imaginal discs, and epistasis analysis places ihog action at or upstream of the negatively acting receptor component, Patched (Ptc). The first of two extracellular fibronectin type III (FNIII) domains of the Ihog protein mediates a specific interaction with Hh protein in vitro, but the second FNIII domain is additionally required for in vivo signaling activity and for Ihog-enhanced binding of Hh protein to cells coexpressing Ptc.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Drosophila melanogaster
- Antigen: Purified recombinant fragment of human IHOG expressed in E. coli.
- Clone: 3G8
- Isotype: Mouse IgG1
- Gene: Q9VM64
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)