Product & ReviewsAntibodies
IκBα Rabbit pAb
Product Details
- Cat. No.
- A11474
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - I?Ba antibody (A11474)
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Description
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
