Product & ReviewsAntibodies
IL-23 Antibody
Product Details
- Cat. No.
- 251562
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Interleukin-23 (IL-23) is a heterodimer cytokine composed of IL-23-alpha and IL12B. IL-23 functions in innate and adaptive immunity. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and has been implicated in autoimmune inflammatory diseases and tumorigenesis.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human IL-23.
- Isotype: Rabbit Ig
- Gene: Q9NPF7
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)