Product & ReviewsAntibodies
IL-4-PE, 4D9, 2 mL, ASR
Product Details
- Cat. No.
- IM2719U
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Interleukin-4 (IL-4) is a monomeric 20 kDa predominantly produced by activated T lymphocytes of the Th2 phenotype, by mast cells and by some antigen-presenting cells. Together with IL-2, IL-4 is an autocrine growth factor for activated T cells and for cytotoxic T cell precursors. IL-4 is a major factor involved in the activation of resting B lymphocytes. Together with IL-13, IL-4 induces isotype switch towards IgE and IgG1 isotypes. Activated CD4+ T cells of the Th1 phenotype produce predominantly IL-2 and Interferon γ, whereas CD4+ T cells of the Th2 phenotype produce IL-4, IL-5, IL6 and IL-10.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: IL-4
- Clone: 4D9
- Conjugate: PE
- Isotype: IgG1
Handling
- Quantity: 2 mL
Applications
- Flow Cytometry (FC)