Product & ReviewsAntibodies
IL1 Receptor Antagonist Antibody
Product Details
- Cat. No.
- 250102
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The interleukin-1 receptor antagonist (IL-1ra) inhibits the activity of IL-1 by binding to the IL-1 receptor but has no IL-1 like activity. IL-1ra has 4 isoforms produced by alternative splicing, only isoform 1 is secreted. The intracellular forms of IL-1ra are predominantly expressed in epithelial cells. Under the name Kineret (Amgen), IL-1ra is used to treat patients with moderate to severe case of active rheumatoid arthritis by slowing the progression of the structural damages. This antibody recognizes human IL-1ra in ELISA.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Recombinant human IL1 receptor antagonist protein
- Clone: KT6
- Isotype: mouse IgG1
- Gene: P18510, NP_776214
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)