IL10 antibody
Product Details
- Cat. No.
- orb221323
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Immunohistochemical staining of mouse skin tissue using IL10 antibody (dilution of primary antibody - 1:100)
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Description
Rabbit polyclonal antibody to interleukin -10 also known as IL10 which belongs to the IL10 super family that is highly expressed by adipocytes and EBV-transformed lymphocyte. This protein is found in the extracellular region. IL10 is a pleiotropic cytokine that has been shown to inhibit activation of; and cytokine generation by; mast cells; as well as survival of; and cytokine production by; eosinophils. It also inhibits antigen-presenting cell (APC) function; including the maturation of dendritic cells; the expression of MHC class II and co-stimulatory molecules and the activation of T-helper-2 cells; IL-10 has been shown to enhance immunoglobulin isotype switching in B cells; and it might promote the induction of IL-10-secreting regulatory T cells.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Clone: NULL
- Conjugate: Unconjugated
- Isotype: IgG
- Gene: 3586
Handling
- Quantity: 100 ?g; 200 ?g
- Storage: Store at 4°C for up to two weeks. For long term storage; aliquot and store at -20°C; avoid freeze/thaw cycles.
- Buffer: 10 mM PBS; 0.02% sodium azide
Applications
- Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
