Product & ReviewsAntibodies
IL17A Rabbit pAb
Product Details
- Cat. No.
- A12454
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - IL17A antibody (A12454)
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Description
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
