IL17A Receptor Rabbit mAb
Product Details
- Cat. No.
- A5163
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - IL17A Receptor Rabbit mAb (A5163)
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Description
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Mouse, Rat
