Product & ReviewsAntibodies
IMPDH2 Rabbit mAb
Product Details
- Cat. No.
- A9208
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - IMPDH2 Rabbit mAb (A9208)
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Description
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
