Product & ReviewsAntibodies

Ini1 Antibody (A-5)

Product Details

Cat. No.
sc-166165
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

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Description

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2ß) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Mouse, Rat
  • Isotype: IgG1

Handling

  • Specificity: 4

Applications

  • ELISA (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
  • Immunoprecipitation (IP)
  • Western Blotting (WB)

Average Rating 3.7

|1Scientists have reviewed this product

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Acceptable results. Pricing is very reasonable.

 

Average Rating 3.7

Application Area:

Western Blot

High intensity separate bands with minimum effort.

Review Date: 4 Dec 2018 | Santa Cruz Biotechnology Inc.

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