Product & ReviewsAntibodies
Insulin-like 3 Antibody
Product Details
- Cat. No.
- 251865
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Insulin-like 3 plays a role in testicular function. Insulin-like 3 is a trophic hormone with a role in testicular descent in fetal life. Insulin-like 3 is a ligand for LGR8 receptor. Insulin-like 3 is a heterodimer of a B chain and an A chain linked by two disulfide bonds. Defects in insulin-like 3 are a cause of cryptorchidism (CRYPTO), also known as impaired testicular descent. CRYPTO is one of the most frequent congenital abnormalities in humans, involving 2-5% of male births. CRYPTO is associated with increased risk of infertility and testicular cancer.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human insulin-like 3.
- Isotype: Rabbit Ig
- Gene: P51460
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)