Product & ReviewsAntibodies

Insulin Receptor-alpha Antibody

Product Details

Cat. No.
250722
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance. This antibody is against the alpha subunit.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human INSR-alpha.
  • Isotype: Rabbit Ig
  • Gene: P06213

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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