Product & ReviewsAntibodies
Integrin Alpha-V Beta-3 Antibody
Product Details
- Cat. No.
- 251672
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Integrin alpha-V/beta-3, also called vitronectin receptor or CD51/CD61, belongs to the integrin protein family that participates in cell adhesion and cell-surface mediated signalling by forming heterodimers of alpha and beta integrin chains. Integrin alpha-V/beta-3 is a receptor for cytoactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins recognize the sequence RGD in a wide array of ligands. Defects in CD61 are a cause of Glanzmann thrombasthenia, a blot clot disorder.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Pig (Swine), Rabbit (Lapine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human integrin alpha-V/beta-3.
- Isotype: Rabbit Ig
- Gene: P06756; P05106
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)
- Immunohistochemistry (IHC)