Integrin alpha V Rabbit mAb
Product Details
- Cat. No.
- A19071
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - Integrin alpha V antibody (A19071)
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Description
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
