Product & ReviewsAntibodies
ISL1 (1B1) Antibody
Product Details
- Cat. No.
- 252885
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
ISL1 (ISL1 transcription factor) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human ISL1 expressed in E. coli.
- Clone: 1B1
- Isotype: Mouse IgG1
- Gene: P61371
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)