Product & ReviewsAntibodies
JAK3 (5H2) Antibody
Product Details
- Cat. No.
- 252930
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
JAK3 (Janus kinase 3) is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this protein are associated with autosomal SCID (severe combined immunodeficiency disease).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Antigen: Purified recombinant fragment of human JAK3 expressed in E. coli.
- Clone: 5H2
- Isotype: Mouse IgG1
- Gene: P52333
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Flow Cytometry (FC)
- Immunofluorescence (IF)
- Western Blotting (WB)