JUNB Rabbit mAb
Product Details
- Cat. No.
- A4848
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - JUNB Rabbit mAb (A4848)
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Description
JunB is one of the components of the Activator Protein-1 (AP-1) transcription complex that have been implicated in the control ofthe G0/G1 transtion in fibroblasts. AP-1 is a collection of dimers formed by members of the Jun-, Fos-, ATF- and Maf multigene families that bind to specific DNA regulatory elements called AP-1/12-O-tetradecanoylphorbol-13-acetate-responsive elements (TREs) and cAMP-responsive elements (CREs). JunB binds to the DNA sequence 5'-TGA[CG]TCA-3', and involves in the regulation of gene activity following the primary growth factor response. It also acts either as a tumor suppressor or as an oncogene depending on the cell and physiopathological context
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human
