Kappa Chain-APC, Polyclonal, F(ab')2 Goat, 0.5 mL, ASR
Product Details
- Cat. No.
- B90420
- Type
- Flow Cytometry Reagents
- Clonality
- Polyclonal
- Host
- Goat
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Description
Kappa (κ) chain is a 25Kd polypeptide that results from papain cleavage of the IgG molecule, encoded by the human immunoglobulin kappa locus (IGK) on chromosome 2. The subunit structure of IgG comprises 2 light chains and 2 heavy chains. Each light chain is composed of two tandem immunoglobulin domains: a) one variable domain (VL) and b) one constant (CL) domain. While the VL show considerable sequence diversity the CL shows internal homology with repeating units. Anti-Kappa antibodies recognize the Kappa light chain of immunoglobulins expressed at the surface of a cellular subpopulation corresponding to approximately 2/3 of mature B lymphocytes in peripheral blood. This light chain is also found on the surface of a sub-population of immature bone marrow B lymphocytes.
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Human
- Antigen: κ Chain
- Clone: Polyclonal-kappa-Goat
- Conjugate: APC
- Isotype: F(ab’)2
Handling
- Quantity: 0.5 mL
Applications
- Flow Cytometry (FC)
