Product & ReviewsAntibodies

Kappa Chain-FITC, Polyclonal, F(ab')2 Rabbit, 100 Tests, CE

Product Details

Cat. No.
B49178
Type
Flow Cytometry Reagents
Clonality
Polyclonal
Host
Rabbit
Beckman Coulter Life Sciences

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Description

Kappa (κ) chain is a 25Kd polypeptide that results from papain cleavage of the IgG molecule, encoded by the human immunoglobulin kappa locus (IGK) on chromosome 2. The subunit structure of IgG comprises 2 light chains and 2 heavy chains. Each light chain is composed of two tandem immunoglobulin domains: a) one variable domain (VL) and b) one constant (CL) domain. While the VL show considerable sequence diversity the CL shows internal homology with repeating units. Anti-Kappa antibodies recognize the Kappa light chain of immunoglobulins expressed at the surface of a cellular subpopulation corresponding to approximately 2/3 of mature B lymphocytes in peripheral blood. This light chain is also found on the surface of a sub-population of immature bone marrow B lymphocytes.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Antigen: κ Chain
  • Clone: Polyclonal-kappa-Rabbit
  • Conjugate: FITC
  • Isotype: F(ab’)2

Handling

  • Quantity: 100 tests

Applications

  • Flow Cytometry (FC)
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