KDM1A rabbit antibody (pAb), sample
Product Details
- Cat. No.
- 61608
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
KDM1A (Lysine (K)-Specific Demethylase 1A) was identified as a subunit of different complexes (such as CtBP, CoREST, NuRD or BRAF35). KDM1A is involved in transcriptional repression of genes through the demethylation ofHistone H3 monomethyl Lys4 and Histone H3 dimethyl Lys4, a methylation site associated with transcriptional activation. KDM1A is also involved in transcriptional activation through the demethylation of Histone H3 monomethyl Lys9 and Histone H3 dimethyl Lys9, a modification often associated with transcriptional repression. KDM1A is also able to demethylate Lys370me1 and Lys370me2 in the regulatory domain of the tumor suppressor p53. KDM1A is a flavin-dependent amine oxidase.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Isotype: IgG
Handling
- Quantity: 10 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Chromatin Immunoprecipitation (ChIP)
- Western Blotting (WB)