Product & ReviewsAntibodies
KIF7 Rabbit pAb
Product Details
- Cat. No.
- A15581
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - KIF7 antibody (A15581)
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Description
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
