Product & ReviewsAntibodies

KLF8 Antibody

Product Details

Cat. No.
252109
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Krueppel-like factor 8 (KLF8) is a transcriptional repressor and activator. KLF8 binds to CACCC-boxes promoter elements. KLF8 also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G1 phase as a downstream target of focal adhesion kinase (FAK). Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G1 phase.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human KLF8.
  • Isotype: Rabbit Ig
  • Gene: O95600

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Western Blotting (WB)
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