Product & ReviewsAntibodies
KLHL12 (2G2) Antibody
Product Details
- Cat. No.
- 253018
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
KLHL12 (Kelch-like protein 12) serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. It is highly expressed in testis and at lower levels in the submandibular salivary gland.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human KLHL12 expressed in E. coli.
- Clone: 2G2
- Isotype: Mouse IgG1
- Gene: Q53G59
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)