[KO Validated] HDAC8 Rabbit pAb
Product Details
- Cat. No.
- A5829
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - HDAC8 Antibody (A5829)
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Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
