[KO Validated] MyD88 Rabbit mAb
Product Details
- Cat. No.
- A19082
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - MyD88 antibody (A19082)
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Description
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human
