Product & ReviewsAntibodies
Ku70 Rabbit mAb
Product Details
- Cat. No.
- A11223
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - Ku70 Rabbit mAb (A11223)
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Description
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human, Mouse
