Lamin A/C mouse antibody (mAb) (Clone 3A6-4C11), sample
Product Details
- Cat. No.
- 39288
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Nuclear lamins are intermediate filament proteins that are the major structural component of the nuclear lamina on the inner surface of the nuclear envelope. Lamins A and C are splicing variants of the Lamin A gene. Lamin A/C expression is a hallmark of embryonic stem cell differentiation. In addition to adding structural integrity to the nucleus, it has also been found that lamins contribute to the makeup of the nuclear matrix. Lamins also help organize interphase chromatin through interactions with several chromatin proteins, including histones, such that alteration in lamin organization results in disruption of DNA replication, transcription and RNA processing.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Hamster, Human, Monkey, Mouse, Rat
- Clone: 3A6-4C11
- Isotype: IgG
Handling
- Quantity: 10 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)