Product & ReviewsAntibodies
LEPR Antibody
Product Details
- Cat. No.
- 252113
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The leptin receptor (LEP-R, CD295) is the receptor for leptin (obesity factor). The binding of leptin mediates signaling through JAK2/STAT3 pathway resulting in the regulation of fat metabolism and, in hematopoietic cells, lymphopoiesis. LEP-R forms a homodimer upon leptin binding, and the phosphorylated receptor binds a number of SH2 domain-containing proteins such as STAT3, PTPN11, and SOCS3.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the human leptin receptor.
- Isotype: Rabbit Ig
- Gene: P48357
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)