Product & ReviewsAntibodies
Leptin Receptor (long) Antibody
Product Details
- Cat. No.
- 250739
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The Leptin receptor (OB receptor, OBR) is the receptor for the obesity factor (leptin). The Leptin Receptor is involved in the regulation of fat metabolism and in lymphopoiesis. The Leptin receptor is closely related to the gp130 signal transducing component common to the IL-6, LIF, CNTF and G-CSF receptors. The Leptin receptor has multiple isoforms (A-E) with isoform B (OBRb) being the long single-pass type I membrane receptor, isoform C (OBRa) carrying a short cytoplasmic domain, and isoform E a shorter secreted form. This antibody is specific for the long form (isoform B).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Dog (Canine), Horse (Equine), Human, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence unique to isoform B (long form) of human Leptin Receptor.
- Isotype: Rabbit Ig
- Gene: P48357
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)