Product & ReviewsAntibodies
LINGO1 Antibody
Product Details
- Cat. No.
- 251546
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (LINGO1) is the functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for inhibition of axonal regeneration by myelin-associated factors. LINGO1 is also a negative regulator of oligodentrocyte differentiation and axonal myelination. LINGO1 acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chicken, Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human LINGO1.
- Isotype: Rabbit Ig
- Gene: Q96FE5
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)