LMO1 Rabbit pAb
Product Details
- Cat. No.
- A7561
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human