LPP (8B3A) Antibody
Product Details
- Cat. No.
- 252748
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
LPP (LIM domain containing preferred translocation partner in lipoma) is an ~80 kDa protein, member of the Zyxin family. LPP localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts, and shuttles to the nucleus where it has transcriptional activation capacity. The Zyxin family of proteins contains five members, Ajuba, LIMD1, LPP, TRIP6 and Zyxin. LPP (LIM-containing lipoma-preferred partner), a LIM domain-containing scaffolding protein contains three LIM domains at its carboxy terminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. The human LPP gene maps to chromosomal location 3q28, and preferentially translocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Hamster, Human, Monkey, Mouse
- Antigen: Purified recombinant fragment of human LPP expressed in E. coli.
- Clone: 8B3A11
- Isotype: Mouse IgG1
- Gene: Q93052
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)