Product & ReviewsAntibodies

LXR-b rabbit antibody (pAb), sample

Product Details

Cat. No.
61178
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Active Motif

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Description

LXR-b (Liver X receptor beta, NR1H2, NER, UNR) is an orphan nuclear receptor and a member of the NR1 receptor family. The LXR receptors (including LXR-a and LXR-b ) bind oxysterols and play key roles in maintaining cholesterol homeostasis in macrophages, primarily by regulating multiple components of the reverse cholesterol transport. They also are potent inhibitors of inflammation and are capable of repressing cytokine and chemokine production by Toll-like receptor (TLR)-activated macrophages. LXR-b is more widely expressed than LXR-a, particularly in the brain.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Isotype: IgG

Handling

  • Quantity: 10 ul
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Chromatin Immunoprecipitation (ChIP)
  • Western Blotting (WB)
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