LYVE-1 Antibody
Product Details
- Cat. No.
- 251673
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE-1) is a ligand-specific transporter trafficking between intracellular organelles and the plasma membrane. LYVE-1 is involved in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). LYVE-1 acts as a hyaluronan transporter either by mediating its uptake for catabolism within lymphatic endothelial cells or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. LYVE-1 is localized to the plasma membrane and in vesicles near extranuclear membranes mainly in endothelial cells lining lymphatic vessels.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human LYVE-1.
- Isotype: Rabbit Ig
- Gene: Q9Y5Y7
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)