Product & ReviewsAntibodies
MADCAM-1 Antibody
Product Details
- Cat. No.
- 250743
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Mucosal addressin cell adhesion molecule 1 (MADCAM-1) is a cell adhesion leukocyte receptor expressed by mucosal venules. MADCAM-1 helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. MADCAM-1 binds to integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. The isoform 2, lacking th emucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strenghthening, independent of L-selectin binding.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse MADCAM-1.
- Isotype: Rabbit Ig
- Gene: Q61826
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)