Magic™ Anti-CCR5 (Phospho S337) monoclonal antibody, clone V14/2
Product Details
- Cat. No.
- CABT-47235MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Human Anti-Human CCR5 (Phospho S337) monoclonal antibody for ELISA; FC; IF; WB. This product is specific for human CD195, a cell surface antigen of approximately 40kD, also known as CCR5. This antibody has been demonstrated to exclusively recognise CD195 phosphorylated at Ser 337, see Pollok-Kopp. Human CD195 is a member of the G protein coupled superfamily of receptors, which acts as a receptor for a number of chemokines including RANTES and also serves as a co-receptor for the entry of HIV into cells. It plays a key role in regulating the activation and migration of leukocytes. CD195 is expressed by a subset of T lymphocytes and by monocytes. Recent studies have shown that upon ligand stimulation, CD195 is rapidly phosphorylated within the C-terminal domain. recognises a band of approximately 40kD on Western blots of RBL-CCR5 cell lysates. Applications：ELISA; FC; IF; WB
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Conjugate: Unconjugated
- Isotype: IgG2b
- Gene: 1234
Handling
- Quantity: 100 μg
- Storage: Store at +4°C or at -20°C if preferred. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)