Magic™ Anti-synaptotagmin 1 (Phospho S309) polyclonal antibody
Product Details
- Cat. No.
- CPBT-66682RS
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Rabbit Anti-Rat synaptotagmin 1 (Phospho S309) polyclonal antibody for WB. This product recognises synaptotagmin 1 phosphorylated at serine 309, a 60kDa member of the synaptotagmin family, expressed in membranes of synaptic vesicles in rostral, phylogenetically younger brain regions and in some endocrine tissues. Ca2+ is bound by synaptogamin whose C2 domains then bind phospholipids, trafficking vesicles to the synaptic membrane and exocytosis. This results in fast synchronous neurotransmitter release. Synaptotagmin also binds neurexins, syntaxin and AP2 independently of Ca2+ binding. Phosphorylation of synaptotagmin by protein kinases is thought to modulate its activity. Western Blotting detects a band of approximately 60kDa in rat cortex cell lysates. Applications：WB
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Mouse, Primate, Rat, Zebrafish
- Conjugate: Unconjugated
- Isotype: Polyclonal IgG
- Gene: 25716
Handling
- Quantity: 100 μl
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)