Magic™ Anti-Y Hydroxylase (Phospho S31) polyclonal antibody
Product Details
- Cat. No.
- CPBT-66687RT
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Rabbit Anti-Rat Y Hydroxylase (Phospho S31) polyclonal antibody for IHC-Fr; IF; WB. This product is specific for Tyrosine Hydroxylase, when phosphorylated at serine 31. Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the biosynthetic pathway of the catecholamines, dopamine (DA), norepinephrine and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain. Phosphorylation of TH has been shown to occur at several serine residues, including serine 8, 19, 31 and 40. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease. Western Blotting detects a band of approximately 60kDa in rat PC-12 cell lysates, following stimulation by Okadaic acid. Applications：IHC-Fr; IF; WB
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Monkey, Mouse, Rat
- Conjugate: Unconjugated
- Isotype: Polyclonal IgG
- Gene: 25085
Handling
- Quantity: 100 μl
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)