Product & ReviewsAntibodies

Mannan-binding Lectin (1E2) Antibody

Product Details

Cat. No.
250354
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars. It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum. This antibody is specific for MBL from human serum or plasma.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: MBL purified from human donor plasma and adsorbed onto aluminum hydroxide.
  • Clone: 1E2
  • Isotype: Mouse IgG1/k
  • Gene: P11226

Handling

  • Quantity: 0.2 mg
  • Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.

Applications

  • ELISA (ELISA)
  • Western Blotting (WB)
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