Mannan-binding Lectin Horse (15C5) Antibody

Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars. It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum. This antibody is specific for human MBL from plasma or serum, but cross-reacts strongly with MBL from horse and swine.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Horse (Equine), Human, Pig (Swine)
• Antigen: MBL purified from human donor plasma and adsorbed onto aluminum hydroxide
• Clone: 15C5
• Isotype: Mouse IgG1/k
• Gene: P11226

• Quantity: 0.2 mg
• Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.

• ELISA (ELISA)