Mannan-binding Lectin Rat (11F11) Antibody
Product Details
- Cat. No.
- 250357
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars. It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum. This antibody is specific for human MBL from plasma or serum, but cross-reacts with MBL from rat.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Rat
- Antigen: MBL purified from human donor plasma and adsorbed onto aluminum hydroxide
- Clone: 11F11
- Isotype: Mouse IgG1/k
- Gene: P11226
Handling
- Quantity: 0.2 mg
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)