Product & ReviewsAntibodies

MAP4K4 (3C7B) Antibody

Product Details

Cat. No.
252792
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: Purified recombinant fragment of MAP4K4(aa400-500) expressed in E. coli.
  • Clone: 3C7B5
  • Isotype: Mouse IgG1
  • Gene: O95819

Handling

  • Quantity: 0.1 ml
  • Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.

Applications

  • Western Blotting (WB)
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