Product & ReviewsAntibodies
MAP4K4 (4H9E) Antibody
Product Details
- Cat. No.
- 252791
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of MAP4K4(aa400-500) expressed in E. coli.
- Clone: 4H9E7
- Isotype: Mouse IgG1
- Gene: O95819
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)