MAPK1 (activated) Antibody
Product Details
- Cat. No.
- 251762
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mitogen-activated protein kinase 1 (MAP kinase 1) is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. MAP kinase 1 acts as a transcriptional repressor. MAP kinase 1 binds to a [GC]AAA[GC] consensus sequence. MAP kinase 1 represses the expression of interferon gamma-induced genes. MAPK1 is activated by phosphorylation on Thr-185 and Tyr-187 in response to insulin and NGF. Both phosphorylations are required for activity. This antibody binds to the diphosphorylated form.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rat, Sheep (Ovine)
- Antigen: Recombinant diphosphorylated human MAPK1.
- Clone: IL-13
- Isotype: Mouse IgG1
- Gene: P28482
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)