Product & ReviewsAntibodies
MAPK10 (10E1) Antibody
Product Details
- Cat. No.
- 252772
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
MAPK10 (c-Jun N-terminal kinase 1 JNK1) responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2. This regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK1 phosphorylates heat shock factor protein 4 (HSF4).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Antigen: Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. coli.
- Clone: 10E4A4
- Isotype: Mouse IgG1
- Gene: P45983; P53779
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)